Template:Throwing Bag synergies

Bagged Item Synergies

Name	Items	Effect	Bag sprite
Guppy Bag	Guppy's Collar, Dead Cat, Guppy's Hairball, Guppy's Head, Guppy's Paw, Guppy's Tail, Guppy's Eye	Thrown bag has a 100% chance to spawn blue flies upon hitting an enemy, while swung bag has 33% chance.
Mom's Bag	Mom's Bottle of Pills, Mom's Bra, Mom's Eye, Mom's Eyeshadow, Mom's Heels, Mom's Key, Mom's Lipstick, Mom's Pad, Mom's Perfume, Mom's Wig, Mom's Underwear, Mom's Pearls, Mom's Razor, Mom's Bracelet, Mom's Ring	10% chance to summon Mom's foot upon hitting an enemy
Drug Bag	Speed Ball, Adrenaline, The Virus, Plan C, Roid Rage, Growth Hormones, Synthoil, Experimental treatment, Euthanasia, Odd Mushroom (thin), Odd mushroom (large), Mini Mush, 1UP, Magic Mush, Blue Cap, Wavy Cap, Mom's Bottle of Pills, Mom's Coin Purse, Placebo, Forget Me Now, Little Baggy, Caffine Pill	The bag spits out bonus colorful tears upon hitting an enemy or a wall, with a chance to spawn a pill
Poop Bag	The Poop, Flush!, Skatole, E. Coli, Brown Nugget, Butt Bombs, Number Two, Hallowed Ground, Dirty Mind, IBS, Montezuma's Revenge	Has a chance to create a random poop upon hitting an enemy (including Tainted ???'s poops)
Fly Bag	Skatole, Halo of Flies, Distant Admiration, Forever Alone, Infestation, The Mulligan, Hive Mind, Smart Fly, BBF, Best Bud, Big Fan, Compost, Friend Zone, Lost Fly, Obsessed Fan, Papa Fly, Jar of Flies, Parasitoid, Angry Fly, Psy Fly, Bot Fly, Fruity Plum, Plum Flute, The Swarm	Has a chance to spawn 2 blue flies upon hitting an enemy
Angel Bag	Dead Dove, Bible, Rosary, Sworn Protector, Guardian Angel, Holy Grail, Holy Mantle, Mitre, Halo, The Relic, Jesus Juice, Act of Contrition, Celtic Cross, Divine Intervention, Immaculate Heart, Blood of the Martyr, Stigmata, Purity, Habit, Sacred Heart, Redemption, Salvation	Has a chance to create a Divine Intervention shield upon hitting an enemy
Devil Bag	The Nail, The Mark, The Pact, Pentagram, Maw of the Void, Abaddon, Eye of the Occult, Lord of the Pit, Sulfur, Athame, Dark Bum, Satanic Bible, The Book of Belial	Has a chance to create a Hungry Soul ghost upon hitting an enemy
Money Bag	Midas' Touch, Eye of Greed, A Dollar, Money = Power, Restock, Head of the Keeper, Greed's Gullet, Coupon, Keeper's Sack, Deep Pockets, Member Card, Piggy Bank, Magic Fingers, Golden Razor	Has a chance to apply Midas freeze effect on hit
Sharp Bag	It Hurts, Blood Oath, Sharp Key, The Pinking Shears, Blood Rights, Guillotine, Scissors, Ventricle Razor, Shard of Glass, Potato Peeler, Backstabber, Sharp Straw, Mom's Razor, Angelic Prism, Apple!	Chance to apply bleeding upon hitting an enemy
Mystic Bag	Sol, Rune Bag, Luna, Mercurius, Venus, Mars, Jupiter, Saturnus, Pluto, Clear Rune, Dream Catcher, Crystal Ball, Magic 8 Ball, Taurus, Aries, Cancer, Leo, Virgo, Libra, Scorpio, Sagittarius, Capricorn, Aquarius, Pisces, Fortune Cookie, Gemini, Tarot Cloth, Zodiac	Chance to spawn a rune or soul stone upon killing an enemy
Spider Bag	Spider Bite, Mutant Spider, Daddy Longlegs, Spider Butt, Spiderbaby, Mom's Wig, Infestation 2, Hive Mind, Juicy Sack, Sissy Longlegs, Box of Spiders, Sticky Bombs, Bursting Sack, Spider Mod, Parasitoid, The Intruder, Keeper's Kin	Chance of spitting out parasitoid tears when hitting an enemy or a wall
Paper Bag	Dead Sea Scrolls, Deck of Cards, Prayer Card, Humbling Bundle, Contract from Below, Bogo Bombs, Starter Deck, Missing Page 2, Blank Card, Divorce Papers, Booster Pack, PHD, False PHD, Card Reading	Has a chance to spawn a random card when killing an enemy
Fart Bag	Butter Bean, The Black Bean, The Bean, Mega Bean, Kidney Bean, Linger Bean, Wait What?, Lil Dumpy, Farting Baby	Has a chance to fart upon hitting an enemy
Bone Bag	Dry Baby, Host Hat, Compound Fracture, Marrow, Slipped Rib, Jaw Bone, Brittle Bones, Bone Spurs	The bag spits out extra bone projectiles upon hitting an enemy
Black Hole Bag	Black Hole, Ocular Rift, Lil Portal	Chance to spawn Ocular Rift portals or, more rarely, a Black Hole upon hitting an enemy
Familiar Bag	Dead Bird, Bird Cage, Succubus, Lil Spewer, BFFS! Any item that contributes to the Conjoined transformation	Leaves a puddle of red creep upon hitting an enemy or a wall
Medical Bag	Vampire Charm, Super Bandage, Blood Bag, IV Bag, Chemical Peel, Anemic, Old Bandage, Leech, Ventricle Razor, Leprosy, Mucormycosis, Hypercoagulation, Hemoptysis, Stye	Has a chance to heal killed enemies and convert them into allies
Organ Bag	Placenta, Isaac's Heart, Varicose Veins, Stem Cells, Blood Clot, Bloodshot Eye, Giant Cell, The Peeper, Vasculitis, Yuck Heart, <3, Yum Heart, Akeldama, Finger!, Eye Sore, Larynx, Belly Button, Empty Vessel, Polydactyly, Empty Heart, Heartbreak, Sacred Heart, Decap Attack, Kidney Stone	When thrown, creates a trail of blood tears behind itself similar to Akeldama
Sandbag	Bloody Gust, Bloody Lust, Lusty Blood	Fires Knockout Drop tears in addition to rocks upon hitting anything
Serving Tray	Candy Heart
Fertilizer Bag	Compost, The Sad Onion, Black Lotus, Dead Onion, Dead Bird, Worm Friend	Has a chance of spawning a friendly Pooter when hitting an enemy.
Bomb Bag	Boom!, Mr. Boom, Kamikaze, Mr. Mega, Pyro, Sad Bombs, Match Book, Bomber Boy, Scatter Bombs, Fast Bombs, Nancy Bombs, Blood Bombs, Brim Bombs, Mama Mega!, Mine Crafter, Glitter Bombs, Rocket in a Jar, Remote Detonator, Best Friend, Ghost Bombs, Butt Bombs, Sticky Bombs	Bag doesn't bounce off walls; When thrown, has a high chance of spawning four bombs that inherit the effects of the items used to create the bag when hitting an enemy. Scatter Bombs increase the amount of bombs spawned by eight in addition to its usual effect of spawning smaller bombs upon detonation.
Generic Status Effect Bag		Causes corresponding effects to enemy upon hitting it

Bagged Item Synergies (item-specific)

• Holy Light - Bag can summon a holy light strike upon hitting anything
• Brimstone - The bag leaves a brimstone beam behind itself when flying
• Dr. Fetus - The bag explodes immediately after first contact with anything
• Spoon Bender - Bag is now homing on enemies
• Spirit Sword - Thrown bag gains piercing, extra bounces, increased damage and shoots magic sword projectiles
• Lost Contact - While swinging, the bag will block projectiles; every blocked projectile lowers its damage multiplier by 0.1, and the swing is canceled when it hits 0%
• Tiny Planet - Bag gains 2 more bounces; rock tears orbit around it and may shoot them in random directions
• Jacob's Ladder - The bag creates electric sparks while launched
• Neptunus - The bag leaves a trail of tears and when hitting something spits a lot of them
• Rubber Cement - The bag bounces more times before ending its flight
• Mom's Knife - The bag pierces through enemies and deals x3 damage
• Death's Touch - The bag pierces through enemies and deals x1.5 more damage
• Mysterious Liquid - The bag leaves a toxic trail of creep and creates a big puddle of it upon hitting anything
• Lemon Mishap /Free Lemonade - The bag leaves a Lemon Mishap pool where it lands
• Technology - The bag shoots lasers while thrown
• Technology 2 - The bag fires a non-stop laser while flying
• Tech. 5 - The bag fires lasers in diferent directions with random effects while flying
• Tech X - While flying, the bag is surrounded by a Tech X ring
• Ipecac - Thrown bag explodes upon hitting an enemy or a wall
• Epic Fetus - The bag shoots rockets while thrown
• The Ludovico Technology - The bag always stays airborne and never falls
• Trisagion - The bag fires Trisagion projectiles while flying
• Playdough Cookie - The bag can inflict different status effects on enemies
• Godhead - The bag leaves Godhead tears on its flight
• Sacred Heart - The bag homes in on enemies, deals x2.3 damage and spills out extra Sacred Heart tears upon hit
• My Reflection - The bag flies back to Cain after some time flying
• Fruit Cake - The bag leaves random effect tears when flying
• Uranus - The bag freezes enemies upon killing them
• Rock Bottom - The bag inherits the item effects of every bag on the ground and gains a damage bonus for each of them
• Sacred Orb - After the bag lands, it shows a timer of 3 seconds, after which the bag explodes with a big radius
• Damocles - Future bags get the effects of an extra item which doesn't take a bag item slot, but Isaac has a 20% chance to die when taking damage while Damocles bag is in the bag queue
• Holy Water - Upon hitting an enemy, creates a holy water freezing puddle
• Lachryphagy - The bag leaves a trail of Lachryphagy tears
• Polyphemus - Increases size and damage of the bag, pierces enemies, but with each enemy pierced, the damage decrease
• Proptosis - The longer the bag flies, the less damage it deals
• A Lump Of Coal - The longer the bag flies, the more damage it deals
• Curse of the Tower - Chance to put a bomb inside the bag while spinning it
• Death Certificate - Upon hitting an enemy, the bag has a 1% chance to spawn a pedestal item, which will increase every time the bag hits an enemy. If it spawns an item or the chance hits 100%, the chance resets.

Regular Item Synergies

• Brimstone - Whenever the bag is swung, a Brimstone ring will appear around Isaac that deals his damage
• Dr. Fetus - Spawns a small Bomb upon hitting anything
• Neptunus - When swinging the bag, tears will be fired in a spiraling pattern
• Tech. 5 - Fires tech 5 laser from Isaac when throwing the bag, which can have random effects (Rubber Cement,Tiny planet, etc)
• Mom's Knife - Upon hitting something with rock projectiles, knives with infinite range that pierce through anything and deal massive damage also fly out
• Ipecac - Upon hitting something, the bag spits Ipecac tears
• Tech X - While swinging the bag, spawns a damaging Tech X ring around Isaac
• Technology 2 - Cain fires a Technology 2 laser non stop in the direction he's looking at when swinging the bag
• Epic Fetus - Rocks dropped from the bag are replaced by flying rockets
• The Ludovico Technology - Creates a tear that can be moved by swinging and throwing bags, similar to the Forgotten synergy
• Trisagion - Rocks spilled from the bag are replaced by 3 trisagion shots
• Spoon Bender - Rocks dropped from the bag home in on enemies
• Lost Contact - Rocks dropped from the bag can block projectiles
• Jacob's Ladder - Rocks spilled from the bag create electric sparks
• Rubber Cement - Rocks spilled from the bag will bounce
• Mysterious Liquid - Rocks spilled from the bag leave toxic creep
• Technology - Rocks spilled from the bag are replaced by fast lasers
• Holy Light - Rocks spilled from the bag can cause a holy light strike
• Haemolacria - Rocks dropped from the bag are replaced by a big haemolacria tear
• Playdough Cookie - Rocks dropped from the bag will inflict different status effects on enemies
• Godhead - Rocks spilled from the bag are replaced by 2 Godhead tears
• Sacred Heart - Rocks from the bag are replaced by Sacred heart tears
• My Reflection - Rocks spilled from the bag fly back to the player
• Fruit Cake - Rocks from the bag can cause random effects
• Uranus - Rocks spilled from the bag can freeze an enemy upon killing it
• Lachryphagy - Tears spilled from the bag work like Lachryphagy tears